Genomics allows individualize treatments for cancer patients, explains Dr. Howard Lim, medical oncologist, BC Cancer.

Breaking down cancer with genomics

Donor funding has played a pivotal role in advancing genomics research

“It was like a miracle.”

Trish Keating was diagnosed with colon cancer in 2010 and after surgery, chemotherapy and radiation treatment, she was told in 2013 when her cancer returned that it was terminal.

After enrolling in the Personalized Onco-Genomics (POG) Program at BC Cancer, the team of experts discovered Trish’s cancer was driven by a specific protein. They then identified and administered an existing blood pressure medication that is known to block pathways to that protein.

The results were rapid and dramatic: eight weeks after starting her new treatment, Trish was tumour-free.

“It’s still so hard to believe,” says Trish. “I was months away from death.”

Trish’s experience is just one example of how genomics – where experts deploy whole genome analysis to inform individual treatment planning for patients – is transforming cancer care for people across B.C.

“The use of genomics is trying to understand the blueprint – what we call the genome – to a cancer, and by understanding that blueprint we can then start to individualize treatments for patients,” says Dr. Howard Lim, medical oncologist, BC Cancer. “Genomics will change not only how we treat cancer, but also how we detect and prevent cancer.”

Cancer genomes are as unique as a fingerprint, and no two genomes are identical. Therefore, says Dr. Lim, cancer treatment can no longer be one-size-fits-all.

“We’re beginning to understand that not all cancers are the same and certain ones respond differently to different treatments, or don’t respond at all to particular treatments,” he says. “With this knowledge we can begin to tailor the type of chemotherapy or targeted agents that we can use for treating specific cancers.”

Dr. Lim says donor funding has played a pivotal role in advancing genomics research, which is also the fundraising focus of BC Cancer Foundation’s Inspiration Gala on Nov. 2.

“The basic science we do to help further all of this research is thanks to donor support – it makes a huge impact to all of us in the clinic,” says Dr. Lim. “In fact, a lot of the research and treatments we’ve moved forward with is because of BC Cancer Foundation donors.”

You can help transform the standard of cancer care with genomically informed treatments for British Columbians facing cancer. Learn more at www.bccancerfoundation.com.

Comments are closed

Just Posted

Sikh millworker lodges human rights complaint against Interfor, again

Mander Sohal, fired from Delta’s Acorn Mill, alleges discrimination based on religion and disability

Developer offers free Tesla 3 with purchase of South Surrey townhome

Century Group’s offer for Viridian development runs through Oct. 31

Police looking for missing teen last seen at Surrey Central bus loop

Surrey RCMP say Daniel Froehlich has been missing since 10 p.m. on Sept. 10

Hot start to BCHL season ‘a huge positive’ for Surrey Eagles

Team stymied by hot Coquitlam Express goalie in home opener

Delta police say no evidence found of shots fired in Tsawwassen

Police received multiple reports of the sound of shots fired in Tsawwassen Sunday night

VIDEO: Liberals make child care pledge, Greens unveil platform on Day 6 of campaign

Green party leader Elizabeth May unveils her party’s platform in Toronto

U.S. student, killed in Bamfield bus crash, remembered as ‘kind, intelligent, talented’

John Geerdes, 18, was one of two UVic students killed in the crash on Friday night

B.C. communities urged to improve access for disabled people

One in four B.C. residents has disability, most want to work

Pedestrian struck and killed by vehicle in Surrey

Investigators were asking anyone who witnessed the incident to come forward

UVic students killed in Bamfield bus crash were from Winnipeg, Iowa City

Authorities said the two victims were a man and a woman, both aged 18

Safety concerns resurface after fatal bus crash on Vancouver Island

Huu-ay-aht First Nations wants a safe route between Bamfield and Port Alberni

National weather forecasters predict average fall, cold winter

The Weather Network says precipitation will about average in most parts of Canada

Two dead, two in critical condition in highway crash near Campbell River

Highway 19 reopened Sunday night after it was closed in both directions

VIDEO: Vancouver Island mayor details emergency response after fatal bus crash

Sharie Minions says she is ‘appalled’ by condition of road where bus crashed

Most Read

l -->